Any mid to high range pc should be able to get very good performance using this guide. Oblivion Reloaded isn't included, but given its popularity I'm going to mention which mods to ignore if you want to use it with this modlist.
This guide assumes that the user has Shivering Isles and KOTN installed, anyone that doesn't can just skip over the DLC related mods though.
An up to date, ENB compatible guide focused on improving Oblivion's visuals without drastically altering anything from its original appearance.